Where there are no Neurologists

Decreasing the Epilepsy Treatment Gap in the Amazon

As much as 80% of the global burden of epilepsy is in the developing world, where there is a higher prevalence of CNS infections, less access to prenatal care, and higher incidence of birth complications. 

Moreover, some 90% of patients with epilepsy in developing countries do not receive appropriate treatment, due to lack of access to neurological diagnosis and care.

The city of Tena is located in Napo Province (pop. 90,000) in the rural Amazon region of Ecuador where the nearest facility with neurological services is located ~200 kilometers away. This distance and a substantial prevalence of poverty prevent patients from obtaining proper diagnosis and treatment of neurological 

Objectives

To develop a sustained  collaboration with a hospital in the rural Amazon region of Ecuador with aim to reduce the epilepsy treatment gap. 

Methods

Unlike surgical projects in developing countries that generally focus on isolated interventions, neurological care requires sustained collaboration.

We established relationship with staff and physicians of the local public Hospital Jose Maria Velasco Ibarra in Tena . In April 2009, a team of 4 neurologists, 1 neurosurgeon, 1 pediatrician, 2 internists, 2 electroencephalography (EEG) technicians, 1 physical therapist and over 20 volunteers (medical students, nurses, and translators both from Ecuador, and the US) saw patients in consultation with the internal medicine and pediatrics staff of the hospital. 

Two portable EEG machines were used. Antiepileptic drugs were supplied by the Ministry of Health free of charge. 

Members of the team gave educational talks on epilepsy management to local physicians and medical students, as well as workshops on seizure first aid and stigma reduction to the local community, students, and first responders. 

Methods

In order to assure sustainability, local pediatricians and general practitioners were actively involved in the consultations and trained in the follow-up care of patients with epilepsy who were begun on treatment during the trip, and email contact and a telemedicine program for further follow-up were established. 

Results

In 7 working days, we evaluated a total of 475 patients with neurological complaints from urban and rural areas of the Napo Province. Diagnoses included but were not limited to seizures, migraine, and developmental delay. 

Of the patients evaluated 45% were males. 41% of patients were age 0-14 years old, 53% were 15-64, and 6% were over age 65 age.  A total of 127 EEGs was performed, 110 of which were abnormal.  101 patients were newly diagnosed with epilepsy by history, physical exam, and EEG, and were started on drug therapy. 28 patients with a prior clinical diagnosis of epilepsy were changed to more appropriate medications based on clinical evaluation and EEG results. 

The epilepsy educational talks were well received by the community and local health providers.

Conclusions

There is a substantial epilepsy treatment gap in this region: only 1 in 4 patients in the cohort evaluated receive appropriate epilepsy treatment.

Collaborations with local hospitals in the developing world are a way to increase access to neurological care for some of the neediest of patients and decrease the epilepsy treatment gap by establishing a partnership between visiting consulting neurologists and local health care systems. 

Acknowledgments

The HydroDot® Disposable EEG Electrode Application System 

Cadwell Laboratories, Inc

MVAP Medical Supplies, Inc.

Rotary Club International ( Westford Rotary Club Massachusetts  – Club Rotario San Rafael – Ecuador) 

Centro Internacional en Neurociencias – CIEN

Ministerio de Salud Publica del Ecuador 

Dirección Provincial de Salud del Tena

Hospital Jose Maria Velasco Ibarra Tena – Ecuador

Fuerza Area Ecuatoriana FAE

Policia Nacional del Ecuador
Clinica de Epilepsia Hospital Metropolitano Quito – Ecuador

ILAE: Visiting Professorship in Epileptology Program

Brigham and Women’s Hospital – Harvard Medical School

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